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Compounds From Bacteria To Control Dengue


Chemicals from the bacteria that drive the female mosquitoes to lay eggs could help prevent the spread of diseases caused by mosquitoes such as dengue and yellow fever, according to researchers in the United States.

Coby Schal and colleagues at North Carolina State University have shown that female mosquitoes of the Aedes aegypti species respond to simple fatty acids, such as tetradekanoat acid, and esters contained in the bacterial cell wall. The researchers plan to use stimulant-stimulants in stimulating female mosquitoes to spend more time on the water mixed with insecticides or biological control agents of insects.

“Another interesting feature of compounds that we’re carefully this can work not only in female mosquitoes but also pregnant female mosquitoes,” says Schal. Pregnant female mosquitoes that are key targets for disease control programs because, unlike male mosquitoes, they suck blood so they can carry and transmit disease.

A mosquito Aedes aegypti females are laying eggs in water mixed with tetradekanoat acid, a stimulant for spawning.

Schal team to identify compounds that stimulate egg laying by memfraksionasi extracts from bacteria found in water. By preparing two cups to be selected by a mosquito – the one containing the compounds of the bacteria and the other containing only water – they were able to identify the most potent stimulant.

These compounds may help the female mosquitoes in deciding whether a site contains enough bacteria that one day his descendants the right to food, says Schal. Female mosquitoes detect the possibility of chemicals through kemoreseptor on foot, or on the organs called the ovipositor egg foundation stone. “Based on the observation of the behavior of female mosquitoes, from the way they were moving in the water, it appears that the ovipositor probably involved,” says Schal.

These compounds contained in various foods, including oils such as coconut oil. “These compounds are very safe compounds, so it will not harm humans, pets or the environment if we put it on an insect trap,” says Schal.

Michael Birkett, from the Centre for Sustainable Pest Rothansted and Disease Management, said the study shows the potential to develop disease control strategies. But he stressed that such strategies will depend on a balanced formulation of these stimulant compounds. “This research is very clear that if the dose or mixture of compounds is not appropriate, then the activity will be lost,” he said.

Source: http://www.rsc.org/chemistryworld/

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